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THIOACETAMIDE TS

Thioacetamide

CAS: 62-55-5

Molecular Formula: C2H5NS

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THIOACETAMIDE TS - Names and Identifiers

Name Thioacetamide
Synonyms CH3CSNH2
Thiacetamide
Thioacetamide
Acetothioamide
Ethanethioamide
Acetamide, thio-
THIOACETAMIDE TS
rcrawastenumberu218
Acetimidic acid, thio-
Rcra waste number U218
CAS 62-55-5
EINECS 200-541-4
InChI InChI=1/C2H5NS/c1-2(3)4/h1H3,(H2,3,4)
InChIKey YUKQRDCYNOVPGJ-UHFFFAOYSA-N

THIOACETAMIDE TS - Physico-chemical Properties

Molecular FormulaC2H5NS
Molar Mass75.13
Density1.37
Melting Point108-112 °C (lit.)
Boling Point111.7±23.0 °C(Predicted)
Flash Point21.4°C
Water Solubility16.3 g/100 mL (25 ºC)
Solubility passes test2%
Vapor Presure22.5mmHg at 25°C
AppearanceWhite crystal
ColorOff-white to slightly beige
Merck14,9319
BRN506006
pKa13.25±0.29(Predicted)
PH5.2 (100g/l, H2O, 20℃)
Storage ConditionInert atmosphere,Room Temperature
StabilityStability Incompatible with water, mineral acids.
SensitiveEasily absorbing moisture
Refractive Index1.5300 (estimate)
MDLMFCD00008070
Physical and Chemical PropertiesColorless or white crystals. Melting point 113-114 ° C, 25 ° C water solubility of 16.3g/100ml, ethanol 26.4g/100ml. Very slightly soluble in benzene, ether. The aqueous solution is quite stable at room temperature or 50 ° C. To 60 ° C., but when hydrogen ions are present, Thio hydrogen is rapidly generated and decomposed. New products sometimes have thiol odor, micro moisture absorption.
UseUsed as a curing agent and cross-linking agent for polymers, rubber additives, pharmaceutical raw materials, etc

THIOACETAMIDE TS - Risk and Safety

Hazard SymbolsT - Toxic
Toxic
Risk CodesR45 - May cause cancer
R22 - Harmful if swallowed
R36/38 - Irritating to eyes and skin.
R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
Safety DescriptionS53 - Avoid exposure - obtain special instructions before use.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. 
S99 -
UN IDs2811
WGK Germany3
RTECSAC8925000
FLUKA BRAND F CODES10
TSCAYes
HS Code29309070
ToxicityMLD orally in rats: 200 mg/kg (Ambrose)

THIOACETAMIDE TS - Reference

Reference
Show more
1. Du, Cuicui, et al. "In situ engineering MoS2 NDs/VS2 lamellar heterostructure for enhanced electrocatalytic hydrogen evolution." ACS Sustainable Chemistry & Engineering 6.11 (2018): 15471-15479.https://doi.org/10.1021/acssuschemeng.8b03929
2. [IF=8.198] Cuicui Du et al."In Situ Engineering MoS2 NDs/VS2 Lamellar Heterostructure for Enhanced Electrocatalytic Hydrogen Evolution."Acs Sustain Chem Eng. 2018;6(11):15471–15479

THIOACETAMIDE TS - Introduction

There is a slight mercaptan odor. Micro moisture absorption. Solubility in water at 25 ℃: 16.3g/100ml, solubility in ethanol: 26.4g/100ml, slightly soluble in ether. The aqueous solution is quite stable at or 50~60°C, but when there are hydrogen ions, it quickly decomposes to produce hydrogen sulfide. The maximum absorption wavelength (in water) is 210, 261, 318nm(logε3 · 66, 4.08, 1.8). Toxic, minimum lethal dose (rat, oral) 200mg/kg. Tests have shown that it has potential carcinogenic effects on experimental animals. Stimulant
Last Update:2022-10-16 17:27:15

THIOACETAMIDE TS - Reference Information

pH range of acid-base indicator discoloration 5.2
NIST chemical information information provided by: webbook.nist.gov (external link)
(IARC) carcinogen classification 2B (Vol. 7, Sup 7) 1987
EPA chemical substance information information provided by: ofmpeb.epa.gov (external link)
organic reagent thioacetamide, also known as ethyl thiamide, is an organic reagent, colorless or white flake crystal. Soluble in water, ethanol, very slightly soluble in benzene, ether, its aqueous solution at room temperature or 50~60 ° C is quite stable, placed for 2~3 weeks, but when there are hydrogen ions, hydrogen sulfide is quickly generated to decompose, but the hydrolysis is accelerated as the acidity or alkalinity of the solution increases and the temperature increases. The hydrolysis reaction equation of thioacetamide in acidic and alkaline solutions is:
in acidic solution: CH3CSNH2 2H2O ----(NH4 ) CH3COO- H2S
In alkaline solution: CH3CSNH2 2oh-nh3 CH3COO- HS-
due to the hydrolysis of H2S or HS-in acidic or alkaline solution, it is often used to replace the toxic and odorous H2S in analytical chemistry, as a component reagent or precipitation reagent for metal cations. The precipitate obtained has good properties and is easy to separate. In addition, it can also be used as an assay reagent for bismuth. Preparation Method: by acetamide and aluminum sulfide heating, acetonitrile and hydrogen sulfide reaction, or acetamide and K3PS4 reaction.
Use used in the production of catalysts, stabilizers, polymerization inhibitors, electroplating additives, photographic drugs, pesticides, dyeing auxiliaries and mineral dressing agents. It is also used as a curing agent, a cross-linking agent, a rubber aid and a pharmaceutical raw material for polymers.
used as vulcanizing agent and crosslinking agent of polymer, rubber auxiliary agent, pharmaceutical raw material, etc.
used as analytical reagent
used for decomposing amino acid copper complex; Used for verification of bismuth; an additive for asymmetric reduction of β-ketoesters with immobilized yeast
was used to decompose amino acid copper complexes. It is also used as a curing agent, a cross-linking agent, a rubber aid and a pharmaceutical raw material for polymers. Hepatotoxins and carcinogens for the isomeric selective reduction of β-keto esters.
production method thioacetamide can be obtained by reacting acetonitrile with hydrogen sulfide or acetamide with phosphorus pentasulfide.
toxic substance data information provided by: pubchem.ncbi.nlm.nih.gov (external link)
Last Update:2024-04-09 21:01:54
THIOACETAMIDE TS
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Tel: 0513-66814854
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Mobile: +86-17551318830
Nantong Reform Petro-Chemical CO., LTD.
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Shanghai Macklin Biochemical Co., Ltd
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Product Name: Thioacetamide solution Visit Supplier Webpage Request for quotation
CAS: 62-55-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
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CAS: 62-55-5
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Email: 18721521379@163.com
Mobile: +86-18721521379
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JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Thioacetamide Request for quotation
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Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
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Guangzhou Yuanda New Material Co.,Ltd
Product Name: Thioacetamide Request for quotation
CAS: 62-55-5
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
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Product Name: Ethanethioamide Request for quotation
CAS: 62-55-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Changsha Changtang import and Export Co., Ltd.
Product Name: Thioacetamide Request for quotation
CAS: 62-55-5
Tel: +86 18942506900
Email: lilyqu@chemoway.com
Mobile: +86 18942506900
QQ: 3182628472 Click to send a QQ message
Wechat: +86 18942506900
WhatsApp: +86 18942506900
Linkedin: +86 18942506900
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Thioacetamide Visit Supplier Webpage Request for quotation
CAS: 62-55-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: Thioacetamide (Standard) Visit Supplier Webpage Request for quotation
CAS: 62-55-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
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THIOACETAMIDE TS
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